GTF2H2 Antikörper

Produktnummer ABIN7862927

Der Maus Monoklonal anti-GTF2H2 Antikörper wird verwendet zum Nachweis von GTF2H2 in Proben von Human. Er wurde validiert für IF und FACS.

Kurzübersicht für GTF2H2 Antikörper (ABIN7862927)

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GTF2H2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-GTF2H2-1B9

Produktdetails anti-GTF2H2 Antikörper

Verwendungszweck: GTF2H2 / BTF2 / TFIIH Basal Transcription Factor Antibody

Spezifität: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFII. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and Mat1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human GTF2H2 protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu GTF2H2

Target: GTF2H2 (General Transcription Factor IIH, Polypeptide 2, 44kDa (GTF2H2))

Andere Bezeichnung: GTF2H2

Hintergrund:

Basic transcription factor 2 44 kDa subunit, BTF2, BTF2-p44, BTF2P44, General transcription factor IIH, polypeptide 2, 44 kDa, T-BTF2P44, TFIIH basal transcription factor complex p44 subunit

HeLa or MCF7 cells.

Molekulargewicht: 44kDa

Gen-ID: 2966, 607501

UniProt: Q13888

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling