CNTF Receptor alpha Antikörper (C-Term)

Produktnummer ABIN929419

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNTF Receptor alpha in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNTF Receptor alpha Antikörper (C-Term) (ABIN929419)

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTF Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CNTF Receptor alpha Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: CNTFR antibody was raised in rabbit using the C terminal of CNTFR as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CNTFR Blocking Peptide, catalog no. 33R-1094, is also available for use as a blocking control in assays to test for specificity of this CNTFR antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CNTF Receptor alpha

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Andere Bezeichnung: CNTFR

Hintergrund: This gene encodes a hematopoeitin/interferon-class receptor belonging to the cytokine superfamily of receptors. The encoded gene product represents the CNTF-specific alpha subunit of a heterotrimer forming the CNTF receptor complex, which also includes LIFR and gp130. The receptor is attached to the membrane by a glycosyl-phosphatidylinositol linkage and contains an immunoglobulin-like C2-type domain and a fibronectin type-III domain. Signal transduction requires that CNTF bind first to this alpha component, which permits the recruitment of gp130 and LIFR beta to form the tripartite receptor complex. Signal transduction stimulates gene expression, cell survival or differentiation in a variety of neuronal cell types. Synonyms: Polyclonal CNTFR antibody, Anti-CNTFR antibody, ciliary neurotrophic factor receptor antibody, MGC1774 antibody.

Pathways: JAK-STAT Signalweg, Feeding Behaviour