BTBD12 Antikörper (N-Term)

Produktnummer ABIN929369

Der Kaninchen Polyklonal Anti-BTBD12-Antikörper wurde für WB validiert. Er ist geeignet, BTBD12 in Proben von Human zu detektieren.

Kurzübersicht für BTBD12 Antikörper (N-Term) (ABIN929369)

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BTBD12 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: BTBD12 antibody was raised in rabbit using the N terminal of BTBD12 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

BTBD12 Blocking Peptide, (ABIN5612371), is also available for use as a blocking control in assays to test for specificity of this BTBD12 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu BTBD12

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Andere Bezeichnung: BTBD12

Hintergrund: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases. Synonyms: Polyclonal BTBD12 antibody, Anti-BTBD12 antibody, BTB, POZ domain containing 12 antibody, KIAA1784 antibody, KIAA1987 antibody, MUS312 antibody, SLX4 antibody.

Pathways: DNA Reparatur