Caspase 10 Antikörper (Middle Region)

Produktnummer ABIN929111

Der Kaninchen Polyklonal anti-Caspase 10 Antikörper wird verwendet zum Nachweis von Caspase 10 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Caspase 10 Antikörper (Middle Region) (ABIN929111)

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 10 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: CASP10 antibody was raised in rabbit using the middle region of CASP10 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: CASP10

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. Synonyms: Polyclonal CASP10 antibody, Anti-CASP10 antibody, caspase 10, apoptosis-related cysteine peptidase antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody.

Pathways: Apoptose, Caspase Kaskade in der Apoptose