Caspase 7 Antikörper (N-Term)

Produktnummer ABIN929110

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Caspase 7 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Caspase 7 Antikörper (N-Term) (ABIN929110)

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 7 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: CASP7 antibody was raised in rabbit using the N terminal of CASP7 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CASP7 Blocking Peptide, (ABIN5612635), is also available for use as a blocking control in assays to test for specificity of this CASP7 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Caspase 7

Target: Caspase 7 (CASP7) (Caspase 7, Apoptosis-Related Cysteine Peptidase (CASP7))

Andere Bezeichnung: CASP7

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. Synonyms: Polyclonal CASP7 antibody, Anti-CASP7 antibody, caspase 7, apoptosis-related cysteine peptidase antibody, CMH-1 antibody, ICE-LAP3 antibody, MCH3 antibody.

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity