CASP5 Antikörper (Middle Region)

Produktnummer ABIN929108

Der Kaninchen Polyklonal anti-CASP5 Antikörper wird verwendet zum Nachweis von CASP5 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CASP5 Antikörper (Middle Region) (ABIN929108)

Target: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CASP5 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: CASP5 antibody was raised in rabbit using the middle region of CASP5 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CASP5 Blocking Peptide, (ABIN5612633), is also available for use as a blocking control in assays to test for specificity of this CASP5 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CASP5

Target: CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

Andere Bezeichnung: CASP5

Hintergrund: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein, this process requires Fas-mediated dephosphorylation of Max. Synonyms: Polyclonal CASP5 antibody, Anti-CASP5 antibody, caspase 5, apoptosis-related cysteine peptidase antibody, ICE(rel)III antibody, ICEREL-III antibody, ICH-3 antibody, MGC141966 antibody.

Pathways: Inflammasome