PDE8A Antikörper (C-Term)

Produktnummer ABIN928993

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDE8A in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PDE8A Antikörper (C-Term) (ABIN928993)

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE8A Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: PDE8 A antibody was raised in rabbit using the C terminal of PDE8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PDE8A Blocking Peptide, (ABIN5615278), is also available for use as a blocking control in assays to test for specificity of this PDE8A antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PDE8A

Target: PDE8A (phosphodiesterase 8A (PDE8A))

Andere Bezeichnung: PDE8A

Hintergrund: Phosphodiesterases (PDEs) regulate the intracellular levels of cAMP and cGMP. These cyclic nucleotides play an important role as second messengers in multiple physiologic processes, including regulation of vascular resistance, cardiac output, visceral motility, immune response, inflammation, neuroplasticity, vision, and reproduction. PDEs comprise a large superfamily of enzymes divided into 10 families. Different PDEs can be distinguished by their structure, tissue expression, localization, substrate specificity, regulation, and sensitivity to PDE inhibitors. Diversity in structure and specificity of function make PDEs promising targets for the pharmacotherapy of diseases modulated by cyclic nucleotide signaling. Synonyms: Polyclonal PDE8A antibody, Anti-PDE8A antibody, phosphodiesterase 8A antibody, FLJ16150 antibody, HsT19550 antibody.

Pathways: cAMP Metabolic Process