GAD Antikörper (N-Term)

Produktnummer ABIN928718

Der Kaninchen Polyklonal Anti-GAD-Antikörper wurde für WB und IHC validiert. Er ist geeignet, GAD in Proben von Human und Maus zu detektieren.

Kurzübersicht für GAD Antikörper (N-Term) (ABIN928718)

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GAD Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: Gad1 antibody was raised in rabbit using the N terminal of Gad1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

Gad1 Blocking Peptide, (ABIN5613700), is also available for use as a blocking control in assays to test for specificity of this Gad1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu GAD

Target: GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))

Andere Bezeichnung: Gad1

Hintergrund: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in  insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with  seizures. Synonyms: Polyclonal Gad1 antibody, Anti-Gad1 antibody, glutamic acid decarboxylase 1 antibody.