SPA17 Antikörper (N-Term)

Produktnummer ABIN928702

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SPA17 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für SPA17 Antikörper (N-Term) (ABIN928702)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPA17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPA17 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: SPA17 antibody was raised in rabbit using the N terminal of SPA17 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SPA17 Blocking Peptide, (ABIN5616350), is also available for use as a blocking control in assays to test for specificity of this SPA17 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Andere Bezeichnung: SPA17

Hintergrund: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22. Synonyms: Polyclonal SPA17 antibody, Anti-SPA17 antibody, sperm autoantigenic protein 17 antibody, SP17 antibody, SP17-1 antibody.