SPA17 Antikörper (N-Term)

Produktnummer ABIN2785535

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SPA17 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Hund, Schwein und Zebrafisch (Danio rerio).

Kurzübersicht für SPA17 Antikörper (N-Term) (ABIN2785535)

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh), Schaf, Hund, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPA17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPA17 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SPA17 Antibody - N-terminal region

Sequenz: MSIPFSNTHY RIPQGFGNLL EGLTREILRE QPDNIPAFAA AYFESLLEKR

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SPA17. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPA17

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53719-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SPA17

Target: SPA17 (Sperm Autoantigenic Protein 17 (SPA17))

Andere Bezeichnung: SPA17

Hintergrund:

Background Information: This gene encodes a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. A retrotransposed pseudogene is present on chromosome 10q22.

Gene Name: Sperm autoantigenic protein 17

Alternative Symbols: CT22, SP17, SP17-1

Protein Name: Sperm surface protein Sp17

Molekulargewicht: 17kDa

Gen-ID: 53340

NCBI Accession: NP_059121

UniProt: Q15506