PAXIP1 Antikörper (N-Term)

Produktnummer ABIN928548

Der Kaninchen Polyklonal anti-PAXIP1 Antikörper (ABIN928548) detektiert spezifisch PAXIP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für PAXIP1 Antikörper (N-Term) (ABIN928548)

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAXIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAXIP1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Frosch, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: PAXIP1 antibody was raised in rabbit using the N terminal of PAXIP1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

PAXIP1 Blocking Peptide, (ABIN5615226), is also available for use as a blocking control in assays to test for specificity of this PAXIP1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PAXIP1

Target: PAXIP1 (PAX Interacting (With Transcription-Activation Domain) Protein 1 (PAXIP1))

Andere Bezeichnung: PAXIP1

Hintergrund: PAXIP1 functions as a key component of the DNA damage response, and phosphoserine or phosphothreonine-specific binding modules. PAXIP1 recognizes substrates phosphorylated by the kinases ataxia telangiectasia-mutated (ATM), ataxia telangiectasia and RAD3-related (ATR) in response to gamma irradiation. It may play a role in PAX2-dependent transcriptional regulation. PAXIP1 plays a role in early development, most probably in cell proliferation. Synonyms: Polyclonal PAXIP1 antibody, Anti-PAXIP1 antibody, PAX interacting, with transcription-activation domain protein 1 antibody, PTIP antibody, TNRC2 antibody, CAGF28 antibody, CAGF29 antibody, PACIP1 antibody, PAXIP1L antibody, FLJ41049 antibody.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response