NUMA1 Antikörper (C-Term)

Produktnummer ABIN928379

Der Kaninchen Polyklonal Anti-NUMA1-Antikörper wurde für WB validiert. Er ist geeignet, NUMA1 in Proben von Human, Maus, Ratte, Huhn und Xenopus laevis zu detektieren.

Kurzübersicht für NUMA1 Antikörper (C-Term) (ABIN928379)

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reaktivität: Human, Maus, Ratte, Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUMA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NUMA1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Ratte (Rattus), Maus, Huhn, Frosch

Aufreinigung: Purified

Immunogen: NUMA1 antibody was raised in rabbit using the C terminal of NUMA1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

NUMA1 Blocking Peptide, (ABIN936841), is also available for use as a blocking control in assays to test for specificity of this NUMA1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu NUMA1

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Andere Bezeichnung: NUMA1

Hintergrund: NuMA is a structural element in maintaining nuclear integrity. A critical spindle pole-associated mechanism, called the END (Emi1/NuMA/dynein-dynactin) network, spatially restricts APC/C activity in early mitosis. The entire coding region and exon-intron boundaries of NuMa were screened in 92 familial breast cancer patients. But the results do not support the role of NuMA variants as breast cancer susceptibility alleles. Synonyms: Polyclonal NUMA1 antibody, Anti-NUMA1 antibody, nuclear mitotic apparatus protein 1 antibody, NUMA antibody.

Pathways: Caspase Kaskade in der Apoptose, Regulation of Actin Filament Polymerization, M Phase