BMP10 Antikörper (N-Term)

Produktnummer ABIN928124

Der Kaninchen Polyklonal Anti-BMP10-Antikörper wurde für WB validiert. Er ist geeignet, BMP10 in Proben von Human und Ratte zu detektieren.

Kurzübersicht für BMP10 Antikörper (N-Term) (ABIN928124)

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMP10 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Purified

Immunogen: Bmp10 antibody was raised in rabbit using the N terminal of Bmp10 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Bmp10 Blocking Peptide, (ABIN939752), is also available for use as a blocking control in assays to test for specificity of this Bmp10 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Andere Bezeichnung: Bmp10

Hintergrund: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth. Synonyms: Polyclonal Bmp10 antibody, Anti-Bmp10 antibody, bone morphogenetic protein 10 antibody, Bmp10 antibody.

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation