BMP10 Antikörper (AA 350-400)

Produktnummer ABIN1387078

Produktdetails anti-BMP10 Antikörper

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Bindungsspezifität: AA 350-400

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BMP10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-BMP10 Antikörper (ABIN1387078)

Wu, Chen, Mi, Chen, Wang, Gao: "Expression analysis of BMP2, BMP5, BMP10 in human colon tissues from Hirschsprung disease patients." in: International journal of clinical and experimental pathology, Vol. 7, Issue 2, pp. 529-36, (2014) (PubMed).

Details zu BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Andere Bezeichnung: BMP10 (BMP10 Produkte)

Synonyme: BMP10 antikoerper, si:dkey-13n15.5 antikoerper, Bmp10 antikoerper, BMP9 antikoerper, BMP-10 antikoerper, bone morphogenetic protein 10 antikoerper, BMP10 antikoerper, bmp10 antikoerper, LOC662386 antikoerper, Bmp10 antikoerper

Hintergrund:

Synonyms: Bone morphogenetic protein 1, BMP-1, BMP1

Background: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.

Gen-ID: 27302

UniProt: O95393

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation