CD8B Antikörper (Middle Region)

Produktnummer ABIN928001

Der Kaninchen Polyklonal anti-CD8B Antikörper wird verwendet zum Nachweis von CD8B in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CD8B Antikörper (Middle Region) (ABIN928001)

Target: CD8B (CD8b Molecule (CD8B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD8B Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: CD8 B antibody was raised in rabbit using the middle region of CD8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CD8B Blocking Peptide, (ABIN940201), is also available for use as a blocking control in assays to test for specificity of this CD8B antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CD8B

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8B

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8B is the CD8 beta chain isoforms. Synonyms: Polyclonal CD8B antibody, Anti-CD8B antibody, CD8b molecule antibody, CD8B1 antibody, LYT3 antibody, Leu2 antibody, Ly3 antibody, MGC119115 antibody.

Pathways: T-Zell Rezeptor Signalweg