CD8B Antikörper (AA 22-170)

Produktnummer ABIN1679102

Der Kaninchen Polyklonal anti-CD8B Antikörper wird verwendet zum Nachweis von CD8B in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CD8B Antikörper (AA 22-170) (ABIN1679102)

Target: CD8B (CD8b Molecule (CD8B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD8B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD8B Antikörper

Bindungsspezifität: AA 22-170

Sequenz: LQQTPAYIKV QTNKMVMLSC EAKISLSNMR IYWLRQRQAP SSDSHHEFLA LWDSAKGTIH GEEVEQEKIA VFRDASRFIL NLTSVKPEDS GIYFCMIVGS PELTFGKGTQ LSVVDFLPTT AQPTKKSTLK KRVCRLPRPE TQKGPLCSP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 22-170 of human CD8B (NP_757362.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CD8B

Target: CD8B (CD8b Molecule (CD8B))

Andere Bezeichnung: CD8B

Hintergrund: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.,CD8B,CD8B1,LEU2,LY3,LYT3,P37,Immunology & Inflammation,CD markers,CD8B

Molekulargewicht: 20 kDa/22 kDa/23 kDa/24 kDa/25 kDa/27 kDa

Gen-ID: 926

UniProt: P10966

Pathways: T-Zell Rezeptor Signalweg