ZBTB33 Antikörper (N-Term)

Produktnummer ABIN927742

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZBTB33 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Huhn und Xenopus laevis.

Kurzübersicht für ZBTB33 Antikörper (N-Term) (ABIN927742)

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZBTB33 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Hund, Huhn, Frosch

Aufreinigung: Purified

Immunogen: ZBTB33 antibody was raised in rabbit using the N terminal of ZBTB33 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ZBTB33 Blocking Peptide, (ABIN5617076), is also available for use as a blocking control in assays to test for specificity of this ZBTB33 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Andere Bezeichnung: ZBTB33

Hintergrund: ZBTB33 is a transcriptional regulator with bimodal DNA-binding specificity. ZBTB33 binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3'. ZBTB33 recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway. It may also activate transcription of a subset of target genes by the recruitment of CTNND2. Synonyms: Polyclonal ZBTB33 antibody, Anti-ZBTB33 antibody, zinc finger and BTB domain containing 33 antibody.