ZBTB33 Antikörper (N-Term)

Produktnummer ABIN6266090

Produktdetails anti-ZBTB33 Antikörper

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZBTB33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: ZBTB33 Antibody detects endogenous levels of total ZBTB33.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human ZBTB33, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu ZBTB33

Target: ZBTB33 (Zinc Finger and BTB Domain Containing 33 (ZBTB33))

Andere Bezeichnung: ZBTB33 (ZBTB33 Produkte)

Synonyme: kaiso antikoerper, ZNF-kaiso antikoerper, ZNF348 antikoerper, AW260253 antikoerper, E130014G12Rik antikoerper, Kaiso antikoerper, Znf-kaiso antikoerper, RGD1566309 antikoerper, zinc finger and BTB domain containing 33 S homeolog antikoerper, zinc finger and BTB domain containing 33 antikoerper, zbtb33.S antikoerper, ZBTB33 antikoerper, Zbtb33 antikoerper

Hintergrund:

Description: Transcriptional regulator with bimodal DNA-binding specificity. Binds to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and also binds to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. May contribute to the repression of target genes of the Wnt signaling pathway. May also activate transcription of a subset of target genes by the recruitment of CTNND2. Represses expression of MMP7 in conjunction with transcriptional corepressors CBFA2T3, CBFA2T2 and RUNX1T1 (PubMed:23251453).

Gene: ZBTB33

Molekulargewicht: 74 kDa

Gen-ID: 10009

UniProt: Q86T24