SMC1A Antikörper (C-Term)

Produktnummer ABIN927735

Dieses Anti-SMC1A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SMC1A in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Zebrafisch (Danio rerio) und Xenopus laevis.

Kurzübersicht für SMC1A Antikörper (C-Term) (ABIN927735)

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Huhn, Zebrafisch (Danio rerio), Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMC1A Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Huhn, Rind (Kuh), Hund, Frosch, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: SMC1 A antibody was raised in rabbit using the C terminal of SMC1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

SMC1A Blocking Peptide, (ABIN5616300), is also available for use as a blocking control in assays to test for specificity of this SMC1A antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SMC1A

Target: SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Andere Bezeichnung: SMC1A

Hintergrund: The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1L2 or the protein encoded by SMC1A gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the SMC1A protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. Synonyms: Polyclonal SMC1A antibody, Anti-SMC1A antibody, structural maintenance of chromosomes 1A antibody, CDLS2 antibody, DKFZp686L19178 antibody, DXS423E antibody, KIAA0178 antibody, MGC138332 antibody, SB1.8 antibody, SMC1 antibody, SMC1L1 antibody, SMC1alpha antibody, SMCB antibody.

Pathways: Stem Cell Maintenance