MAF Antikörper (N-Term)

Produktnummer ABIN927724

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MAF in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn und Hund.

Kurzübersicht für MAF Antikörper (N-Term) (ABIN927724)

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Zebrafisch (Danio rerio), Huhn, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAF Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Huhn, Hund, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: MAF antibody was raised in rabbit using the N terminal of MAF as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

MAF Blocking Peptide, (ABIN5614625), is also available for use as a blocking control in assays to test for specificity of this MAF antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu MAF

Target: MAF (V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog (Avian) (MAF))

Andere Bezeichnung: MAF

Hintergrund: MAF acts as a transcriptional activator or repressor. It is involved in embryonic lens fiber cell development. It recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. MAF is also involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. When overexpressed, MAF represses anti-oxidant reponse element (ARE)-mediated transcription. It may be involved either as an oncogene or as a tumor suppressor, depending on the cell context. Synonyms: Polyclonal MAF antibody, Anti-MAF antibody, v-maf musculoaponeurotic fibrosarcoma oncogene homolog, avian antibody, MGC71685 antibody.