SNF8 Antikörper (N-Term)

Produktnummer ABIN927326

Der Kaninchen Polyklonal Anti-SNF8-Antikörper wurde für WB und IHC validiert. Er ist geeignet, SNF8 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis und Huhn zu detektieren.

Kurzübersicht für SNF8 Antikörper (N-Term) (ABIN927326)

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Xenopus laevis, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNF8 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Frosch, Rind (Kuh), Hund, Huhn, Zebrafisch (Brachydanio rerio)

Aufreinigung: Purified

Immunogen: EAP30 antibody was raised in rabbit using the N terminal of EAP30 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

EAP30 Blocking Peptide, (ABIN5613289), is also available for use as a blocking control in assays to test for specificity of this EAP30 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu SNF8

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Andere Bezeichnung: EAP30

Hintergrund: ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia. In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25, and VPS36 form ESCRT-II, a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor. Synonyms: Polyclonal EAP30 antibody, Anti-EAP30 antibodyDot3 antibody, EAP30 antibody, VPS22 antibody.