SNF8 Antikörper (N-Term)

Produktnummer ABIN2777633

Der Kaninchen Polyklonal anti-SNF8 Antikörper wird verwendet zum Nachweis von SNF8 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio) und Ziege. Er wurde validiert für WB und IHC.

Kurzübersicht für SNF8 Antikörper (N-Term) (ABIN2777633)

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SNF8 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Snf8 Antibody - N-terminal region

Sequenz: GTVLAEDQLA QMSKQLDMFK TNLEEFASKH KQEIRKNPEF RVQFQDMCAT

Homologie: Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Snf8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP32857-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SNF8

Target: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Andere Bezeichnung: Snf8

Hintergrund:

Background Information: Snf8 is required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is a component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL.

Gene Name: SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)

Alternative Symbols: D11moh34, RGD1310144

Protein Name: Vacuolar-sorting protein SNF8

Molekulargewicht: 28kDa

Gen-ID: 287645

NCBI Accession: NP_001007805

UniProt: Q5RK19