Glucocorticoid Receptor Antikörper (N-Term)

Produktnummer ABIN927317

Der Kaninchen Polyklonal Anti-Glucocorticoid Receptor-Antikörper wurde für WB validiert. Er ist geeignet, Glucocorticoid Receptor in Proben von Human zu detektieren.

Kurzübersicht für Glucocorticoid Receptor Antikörper (N-Term) (ABIN927317)

Target: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glucocorticoid Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Glucocorticoid Receptor Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: NR3 C1 antibody was raised in rabbit using the N terminal of NR3 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

NR3C1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NR3C1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Glucocorticoid Receptor

Target: Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))

Andere Bezeichnung: NR3C1

Hintergrund: NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Synonyms: Polyclonal NR3C1 antibody, Anti-NR3C1 antibody, nuclear receptor subfamily 3, group C, member 1, glucocorticoid receptor antibody, GCCR antibody, GCR antibody, GR antibody, GRL antibody.

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process