TYK2 Antikörper (C-Term)

Produktnummer ABIN927289

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TYK2 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TYK2 Antikörper (C-Term) (ABIN927289)

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TYK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TYK2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: TYK2 antibody was raised in rabbit using the C terminal of TYK2 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu TYK2

Target: TYK2 (Tyrosine Kinase 2 (TYK2))

Andere Bezeichnung: TYK2

Hintergrund: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. Synonyms: Polyclonal TYK2 antibody, Anti-TYK2 antibody, tyrosine kinase 2 antibody, JTK1 antibody.

Pathways: JAK-STAT Signalweg, Hepatitis C