CHRNA4 Antikörper (N-Term)

Produktnummer ABIN926962

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CHRNA4 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh) und Huhn.

Kurzübersicht für CHRNA4 Antikörper (N-Term) (ABIN926962)

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CHRNA4 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Huhn

Aufreinigung: Purified

Immunogen: CHRNA4 antibody was raised in rabbit using the N terminal of CHRNA4 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CHRNA4 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CHRNA4 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CHRNA4

Target: CHRNA4 (Cholinergic Receptor, Nicotinic, alpha 4 (CHRNA4))

Andere Bezeichnung: CHRNA4

Hintergrund: CHRNA4 is a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Synonyms: Polyclonal CHRNA4 antibody, Anti-CHRNA4 antibody, cholinergic receptor, nicotinic, alpha 4 antibody, BFNC antibody, EBN antibody, EBN1 antibody, NACRA4 antibody.

Pathways: Synaptic Membrane