CXCL12 Antikörper (Middle Region)

Produktnummer ABIN926925

Dieses Anti-CXCL12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CXCL12 in WB. Geeignet für Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Huhn und Xenopus laevis.

Kurzübersicht für CXCL12 Antikörper (Middle Region) (ABIN926925)

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Huhn, Xenopus laevis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCL12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CXCL12 Antikörper

Bindungsspezifität: Middle Region

Kreuzreaktivität: Maus, Ratte (Rattus), Frosch, Schwein, Hund, Huhn, Rind (Kuh)

Aufreinigung: Purified

Immunogen: CXCL12 antibody was raised in rabbit using the middle region of CXCL12 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CXCL12 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CXCL12 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CXCL12

Target: CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))

Andere Bezeichnung: CXCL12

Hintergrund: Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group. Synonyms: Polyclonal CXCL12 antibody, Anti-CXCL12 antibody, chemokine, C-X-C motif ligand 12, stromal cell-derived factor 1 antibody.

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events, Negative Regulation of intrinsic apoptotic Signaling