RAD9A Antikörper (C-Term)

Produktnummer ABIN926900

Der Kaninchen Polyklonal Anti-RAD9A-Antikörper wurde für WB validiert. Er ist geeignet, RAD9A in Proben von Human und Ratte zu detektieren.

Kurzübersicht für RAD9A Antikörper (C-Term) (ABIN926900)

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD9A Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Purified

Immunogen: RAD9 A antibody was raised in rabbit using the C terminal of RAD9 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

RAD9A Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this RAD9A antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu RAD9A

Target: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Andere Bezeichnung: RAD9A

Hintergrund: RAD9A is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. Synonyms: Polyclonal RAD9A antibody, Anti-RAD9A antibody, RAD9 homolog A, S. pombe antibody, RAD9 antibody.

Pathways: Positive Regulation of Response to DNA Damage Stimulus