BIRC7 Antikörper (Middle Region)

Produktnummer ABIN926876

Der Kaninchen Polyklonal Anti-BIRC7-Antikörper wurde für WB validiert. Er ist geeignet, BIRC7 in Proben von Human zu detektieren.

Kurzübersicht für BIRC7 Antikörper (Middle Region) (ABIN926876)

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BIRC7 Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: BIRC7 antibody was raised in rabbit using the middle region of BIRC7 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

BIRC7 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this BIRC7 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Andere Bezeichnung: BIRC7

Hintergrund: BIRC7 protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1. In vitro, inhibits caspase-3 and proteolytic activation of pro-caspase-9. Isoform 1 blocks staurosporine-induced apoptosis. Isoform 2 blocks etoposide-induced apoptosis. Synonyms: Polyclonal BIRC7 antibody, Anti-BIRC7 antibody, baculoviral IAP repeat-containing 7, livin antibody, KIAP antibody, LIVIN antibody, ML-IAP antibody, MLIAP antibody, RNF50 antibody.