BIRC7 Antikörper (C-Term)

Produktnummer ABIN358607

Produktdetails anti-BIRC7 Antikörper

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIRC7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to BIRC7.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/50 - 1/200. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Referenzen für anti-BIRC7 Antikörper (ABIN358607)

Faruk, Ibrahim, Aminu, Adamu, Abdullahi, Suleiman, Rafindadi, Mohammed, Iliyasu, Idoko, Saidu, Randawa, Musa, Ntekim, Shah, Abubakar, Adoke, Manko, Awasum: "Prognostic significance of BIRC7/Livin, Bcl-2, p53, Annexin V, PD-L1, DARC, MSH2 and PMS2 in colorectal cancer treated with FOLFOX chemotherapy with or without aspirin." in: PLoS ONE, Vol. 16, Issue 1, pp. e0245581, (2021) (PubMed).

Details zu BIRC7

Target: BIRC7 (Baculoviral IAP Repeat-Containing 7 (BIRC7))

Andere Bezeichnung: BIRC7 / LIVIN (BIRC7 Produkte)

Synonyme: KIAP antikoerper, LIVIN antikoerper, ML-IAP antikoerper, MLIAP antikoerper, RNF50 antikoerper, EIAP/XLX antikoerper, XLX antikoerper, kiap antikoerper, livin antikoerper, ml-iap antikoerper, mliap antikoerper, rnf50 antikoerper, xEIAP antikoerper, RGD1562883 antikoerper, zgc:165605 antikoerper, E130019N06 antikoerper, Livin antikoerper, birc7 antikoerper, bird7a antikoerper, xEIAP/XLX antikoerper, xlx antikoerper, EIAP/XLX-B antikoerper, birc7b antikoerper, baculoviral IAP repeat containing 7 antikoerper, baculoviral IAP repeat-containing 7 antikoerper, baculoviral IAP repeat-containing 7 (livin) antikoerper, baculoviral IAP repeat containing 7 S homeolog antikoerper, baculoviral IAP repeat containing 7 L homeolog antikoerper, BIRC7 antikoerper, birc7 antikoerper, Birc7 antikoerper, birc7.S antikoerper, birc7.L antikoerper

Hintergrund: BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.Synonyms: Baculoviral IAP repeat-containing protein 7, KIAP, Kidney inhibitor of apoptosis protein, Livin, MLIAP, Melanoma inhibitor of apoptosis protein, RING finger protein 50, RNF50

Gen-ID: 79444, 5874

UniProt: Q96CA5