VPS4B Antikörper (N-Term)

Produktnummer ABIN926774

Der Kaninchen Polyklonal Anti-VPS4B-Antikörper wurde für WB validiert. Er ist geeignet, VPS4B in Proben von Human zu detektieren.

Kurzübersicht für VPS4B Antikörper (N-Term) (ABIN926774)

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VPS4B Antikörper

Bindungsspezifität: N-Term

Aufreinigung: Purified

Immunogen: VPS4 B antibody was raised in rabbit using the N terminal of VPS4 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

VPS4B Blocking Peptide, catalog no. 33R-10320, is also available for use as a blocking control in assays to test for specificity of this VPS4B antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu VPS4B

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Andere Bezeichnung: VPS4B

Hintergrund: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18, the gene for the other resides on chromosome 16. Synonyms: Polyclonal VPS4B antibody, Anti-VPS4B antibody, vacuolar protein sorting 4 homolog B, S. cerevisiae antibody, MIG1 antibody, SKD1 antibody, SKD1B antibody, VPS4-2 antibody.

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events