VASP Antikörper (Middle Region)

Produktnummer ABIN926692

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VASP in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für VASP Antikörper (Middle Region) (ABIN926692)

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VASP Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: VASP antibody was raised in rabbit using the middle region of VASP as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

VASP Blocking Peptide, (ABIN935974), is also available for use as a blocking control in assays to test for specificity of this VASP antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Andere Bezeichnung: VASP

Hintergrund: Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG. Synonyms: Polyclonal VASP antibody, Anti-VASP antibody, vasodilator-stimulated phosphoprotein antibody.

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation