Endothelin 3 Antikörper (C-Term)

Produktnummer ABIN926685

Der Kaninchen Polyklonal anti-Endothelin 3 Antikörper (ABIN926685) detektiert spezifisch Endothelin 3 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Endothelin 3 Antikörper (C-Term) (ABIN926685)

Target: Endothelin 3 (EDN3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endothelin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Endothelin 3 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: EDN3 antibody was raised in rabbit using the C terminal of EDN3 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

EDN3 Blocking Peptide, (ABIN940397), is also available for use as a blocking control in assays to test for specificity of this EDN3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Endothelin 3

Target: Endothelin 3 (EDN3)

Andere Bezeichnung: EDN3

Hintergrund: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed. Synonyms: Polyclonal EDN3 antibody, Anti-EDN3 antibody, endothelin 3 antibody, ET3 antibody, MGC15067 antibody, MGC61498 antibody.

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones