CDK6 Antikörper (C-Term)

Produktnummer ABIN925995

Dieses Anti-CDK6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDK6 in WB. Geeignet für Human, Maus, Rind (Kuh) und Hund.

Kurzübersicht für CDK6 Antikörper (C-Term) (ABIN925995)

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Reaktivität: Human, Maus, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CDK6 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Rind (Kuh), Hund

Immunogen: CDK6 antibody was raised in rabbit using the C terminal of CDK6 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.625 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

CDK6 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CDK6 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu CDK6

Target: CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

Andere Bezeichnung: CDK6

Hintergrund: CDK6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Synonyms: Polyclonal CDK6 antibody, Anti-CDK6 antibody, cyclin-dependent kinase 6 antibody, MGC59692 antibody, PLSTIRE antibody.

Pathways: Zellzyklus, Mitotic G1-G1/S Phases