BCL2L1 Antikörper (N-Term)

Produktnummer ABIN925766

Der Kaninchen Polyklonal anti-BCL2L1 Antikörper wird verwendet zum Nachweis von BCL2L1 in Proben von Human, Maus, Ratte, Schwein, Hund, Rind (Kuh) und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für BCL2L1 Antikörper (N-Term) (ABIN925766)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BCL2L1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Hund, Maus, Ratte (Rattus), Kaninchen, Rind (Kuh), Schwein

Immunogen: BCL2 L1 antibody was raised in rabbit using the N terminal of BCL2 1 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

BCL2L1 Blocking Peptide, (ABIN5612302), is also available for use as a blocking control in assays to test for specificity of this BCL2L1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Andere Bezeichnung: BCL2L1

Hintergrund: BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis.The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Synonyms: Polyclonal BCL2L1 antibody, Anti-BCL2L1 antibody, BCL2-like 1 antibody, BCL-XL/S antibody, BCL2L antibody, BCLX antibody, Bcl-X antibody, DKFZp781P2092 antibody, bcl-xL antibody, bcl-xS antibody.

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling