F11R
Reaktivität: Human
WB
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Flow cytometry: Use at a 1:10 dilution. Immunofluorescence: (fixed cells)
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
1 mL of 100 µg/mL 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Target
F11R
(F11 Receptor (F11R))
Andere Bezeichnung
JAM-1
Hintergrund
Junctional adhesion molecule-1 (JAM-1) is a cell adhesion molecule (CAM). JAM-1 is a member of the immunoglobulin superfamily found on the surface of mouse platelets and at intercellular juctions of endothelial cells and epithelial cells. JAM-1 belongs together with JAM-2 and JAM-3 to a family of adhesion proteins with a V-C2 immunoglobulin domain organization. JAM plays an important role in tight junctions where it is involved in cell-to-cell adhesion through homophilic interaction. It co-distributes with other tight junction components such as ZO-1, 7H6 antigen, cingulin and occludin. In humans JAM-1 plays a role in platelet aggregation, secretion, adhesion and spreading. Synonyms: Platelet F11-Receptor (F11R)