TRERF1 Antikörper (AA 101-200) (Cy7)

Produktnummer ABIN918580

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRERF1 in IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TRERF1 Antikörper (AA 101-200) (Cy7) (ABIN918580)

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRERF1 Antikörper ist konjugiert mit Cy7

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-TRERF1 Antikörper (Cy7)

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TReP132/RAPA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu TRERF1

Target: TRERF1 (Transcriptional Regulating Factor 1 (TRERF1))

Andere Bezeichnung: TReP132

Hintergrund:

Synonyms: BCAR2, Breast cancer anti estrogen resistance 2, Breast cancer anti-estrogen resistance 2, RAPA, rapa 1, rapa 2, rapa1, rapa2, RP1 139D8.5, Transcriptional regulating factor 1, Transcriptional regulating protein 132, Transcriptional-regulating factor 1, Transcriptional-regulating protein 132, TREF1_HUMAN, TReP 132, TREP132, TRERF1, Zinc finger protein rapa, Zinc finger transcription factor TReP 132, Zinc finger transcription factor TReP-132.

Background: Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.

Gen-ID: 55809

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding