PNKP Antikörper (AA 51-160) (AbBy Fluor® 350)
Kurzübersicht für PNKP Antikörper (AA 51-160) (AbBy Fluor® 350) (ABIN911593)
Target
Alle PNKP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 51-160
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Homologie
- Human,Mouse,Rat,Dog,Cow,Sheep
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PNK1/PNKP
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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Andere Bezeichnung
- PNK1/PNKP
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Hintergrund
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Synonyms: Bunctional polynucleotide phosphatase/kinase, DEM 1, DEM1, DNA 5' kinase/3' phosphatase, PNK 1, PNK, PNK1, PNKP, Polynucleotide 5' hydroxyl kinase, Polynucleotide kinase 3 prime phosphatase, Polynucleotide kinase 3' phosphatase, Polynucleotide Kinase, PNKP_HUMAN.
Background: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
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Gen-ID
- 11284
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Pathways
- DNA Reparatur, Nucleotide Phosphorylation
Target
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