PLAG1 Antikörper (AbBy Fluor® 555)
Kurzübersicht für PLAG1 Antikörper (AbBy Fluor® 555) (ABIN911307)
Target
Alle PLAG1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human PLAG1
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Isotyp
- IgG
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anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 2-99) antibody
PLAG1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 1F11 unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 2-99) antibodyPLAG1 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 3B7 unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 51-150) antibodyPLAG1 Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) antibodyPLAG1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 8-35), (N-Term) antibodyPLAG1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB31388 unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 33-288) antibodyPLAG1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (C-Term) antibodyPLAG1 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Hund, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (AA 2-99) antibodyPLAG1 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (N-Term) antibodyPLAG1 Reaktivität: Human, Meerschweinchen, Kaninchen, Hund, Pferd, Rind (Kuh), Schwein, Fledermaus, Huhn, Affe, Xenopus laevis WB Wirt: Kaninchen Polyclonal unconjugated
anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (C-Term) antibodyPLAG1 Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- IF(IHC-P) 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- PLAG1 (Pleiomorphic Adenoma Gene 1 (PLAG1))
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Andere Bezeichnung
- Plag1
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Hintergrund
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Synonyms: PSA, SGPA, ZNF912, Zinc finger protein PLAG1, Pleiomorphic adenoma gene 1 protein, PLAG1
Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia.
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Gen-ID
- 5324
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UniProt
- Q6DJT9
Target
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