PLAG1 Antikörper (Pleiomorphic Adenoma Gene 1) (N-Term)

Details for Product anti-PLAG1 Antibody No. ABIN2780443, Anbieter: Anmelden zum Anzeigen
Antigen
  • PLAG1
  • MGC152687
  • PSA
  • SGPA
  • ZNF912
  • PLAG1 zinc finger
  • pleiomorphic adenoma gene 1
  • PLAG1
  • plag1
  • Plag1
Epitop
N-Term
11
9
8
3
3
3
3
3
3
2
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
69
38
37
3
3
2
2
2
1
1
1
1
1
Wirt
Kaninchen
63
7
Klonalität
Polyklonal
Konjugat
Dieser PLAG1 Antikörper ist unkonjugiert
4
4
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Applikation
Western Blotting (WB)
44
26
25
6
3
3
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human PLAG1
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN981833.
Sequenz MATVIPGDLS EVRDTQKVPS GKRKRGETKP RKNFPCQLCD KAFNSVEKLK
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against PLAG1. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Plasmids, Primers & others Plasmide, Primers & weitere PLAG1 products on genomics-online (e.g. as negative or positive controls)
Antigen Pleiomorphic Adenoma Gene 1 (PLAG1)
Andere Bezeichnung PLAG1 (PLAG1 Antibody Abstract)
Hintergrund PLAG1 is a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas.Pleomorphic adenoma gene 1 encodes a zinc finger protein with 2 putative nuclear localization signals. PLAG1, which is developmentally regulated, has been shown to be consistently rearranged in pleomorphic adenomas of the salivary glands. PLAG1 is activated by the reciprocal chromosomal translocations involving 8q12 in a subset of salivary gland pleomorphic adenomas. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: PSA, SGPA, ZNF912
Protein Interaction Partner: SMAD3, ALB, PIAS4, PIAS2, PIAS1, SUMO1, KPNA2,
Protein Size: 500
Molekulargewicht 56 kDa
Gen-ID 5324
NCBI Accession NM_002655, NP_002646
UniProt Q6DJT9
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 500 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (N-Term) antibody (ABIN2780443) WB Suggested Anti-PLAG1 Antibody Titration: 0.2-1 ug/ml Positive Control: Hela cel...
Western Blotting (WB) image for anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (N-Term) antibody (ABIN2780443) Host: Rabbit Target Name: PLAG1 Sample Type: Human Fetal Heart Antibody Dilutio...
Western Blotting (WB) image for anti-Pleiomorphic Adenoma Gene 1 (PLAG1) (N-Term) antibody (ABIN2780443) Host: Rabbit Target Name: PLAG1 Sample Type: Human Fetal Heart Antibody Dilutio...
Allgemeine Veröffentlichungen Persson, Winnes, Andrén, Wedell, Dahlenfors, Asp, Mark, Enlund, Stenman: "High-resolution array CGH analysis of salivary gland tumors reveals fusion and amplification of the FGFR1 and PLAG1 genes in ring chromosomes." in: Oncogene, Vol. 27, Issue 21, pp. 3072-80, 2008 (PubMed).

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