NLRP7 Antikörper (AA 901-980) (HRP)

Produktnummer ABIN908483

Der Kaninchen Polyklonal Anti-NLRP7-Antikörper wurde für ELISA, WB, IHC (p) und IHC (fro) validiert. Er ist geeignet, NLRP7 in Proben von Human zu detektieren.

Kurzübersicht für NLRP7 Antikörper (AA 901-980) (HRP) (ABIN908483)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP7 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-NLRP7 Antikörper (HRP)

Bindungsspezifität: AA 901-980

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NLRP7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Andere Bezeichnung: NLRP7

Hintergrund:

Synonyms: CLR19.4, FLJ94610, HYDM, NACHT, leucine rich repeat and PYD containing 7, NACHT, LRR and PYD containing protein 7, NACHT, LRR and PYD domains containing protein 7, NACHT, LRR and PYD domains-containing protein 7, NALP7, NALP7_HUMAN, NLR family, pyrin domain containing 7, NLRP7, NOD12, Nucleotide-binding oligomerization domain protein 12, Nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7, PAN7, PYPAF3, PYRIN-containing APAF1-like protein 3.

Background: This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Gen-ID: 199713

Pathways: Inflammasome