MAS1 Antikörper (AbBy Fluor® 647)
Kurzübersicht für MAS1 Antikörper (AbBy Fluor® 647) (ABIN905732)
Target
Alle MAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Kreuzreaktivität
- Human, Maus
-
Homologie
- Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human MAS1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
FCM 1:20-100
IF(IHC-P) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- MAS1 (MAS1 Oncogene (MAS1))
-
Andere Bezeichnung
- Mas1
-
Hintergrund
-
Synonyms: MAS, MGRA, Proto-oncogene Mas, MAS1
Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
-
Gen-ID
- 4142
-
UniProt
- P04201
-
Pathways
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
Target
-