INSRR Antikörper (PE)

Produktnummer ABIN902841

Dieses Anti-INSRR-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von INSRR in IF (p). Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für INSRR Antikörper (PE) (ABIN902841)

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSRR Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-INSRR Antikörper (PE)

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Kreuzreaktivität: Ratte (Rattus), Hund, Schwein, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu INSRR

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Andere Bezeichnung: INSRR

Hintergrund: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesnﾒt bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

Molekulargewicht: 144kDa

Gen-ID: 3645

Pathways: RTK Signalweg