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HAX1 Antikörper (AA 191-279) (Biotin)

This anti-HAX1 antibody (ABIN900156) is a Rabbit Polyclonal antibody detecting HAX1 in WB, ELISA, IHC (p), IHC (fro). Suitable for Human.
Produktnummer ABIN900156

Quick Overview for HAX1 Antikörper (AA 191-279) (Biotin) (ABIN900156)

Target

Alle HAX1 Antikörper anzeigen
HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reaktivität

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Human

Wirt

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Kaninchen

Klonalität

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Polyklonal

Konjugat

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Dieser HAX1 Antikörper ist konjugiert mit Biotin

Applikation

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Bindungsspezifität

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    AA 191-279

    Homologie

    Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human HAX1

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C for 12 months.

    Haltbarkeit

    12 months
  • Target

    HAX1 (HCLS1 Associated Protein X-1 (HAX1))

    Andere Bezeichnung

    HAX1

    Hintergrund

    Synonyms: HAX 1, Hax1a, HCLS1 and PKD2 associated protein, HCLS1 associated protein, HCLS1 associated protein X 1, HCLSBP1, HS 1 associated protein X 1, HS 1 binding protein, HS1 associating protein X 1, HS1 binding protein 1, HS1 binding protein, HS1BP1, SCN3.

    Background: RelevanceHAX1 associates with HS1, binding to its N-terminal region. It is also known to associate with PKD2 (involved in polycystic kidney disease) and with cortactin/EMS1. HAX1 is also reported to bind to hairpin structures in vimentin and DNA polymerase beta mRNAs, so may play a role in mRNA stability and transport. It may also function in promoting cell survival. Defects in HAX1 are the cause of autosomal recessive severe congenital neutropenia 3 (SCN3) also called Kostmann disease.

    Gen-ID

    10456

    Pathways

    Regulation of Actin Filament Polymerization
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