HAX1 Antikörper (C-Term)

Produktnummer ABIN6262152

Produktdetails anti-HAX1 Antikörper

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: HAX1 Antibody detects endogenous levels of total HAX1.

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human HAX1, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu HAX1

Target: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Andere Bezeichnung: HAX1 (HAX1 Produkte)

Synonyme: HAX1 antikoerper, hax1 antikoerper, HCLSBP1 antikoerper, HS1BP1 antikoerper, SCN3 antikoerper, HAX-1 antikoerper, Hs1bp1 antikoerper, HSP1BP-1 antikoerper, SIG-111 antikoerper, Silg111 antikoerper, mHAX-1s antikoerper, HCLS1 associated protein X-1 antikoerper, HCLS1 associated X-1 antikoerper, HAX1 antikoerper, hax1 antikoerper, Hax1 antikoerper

Hintergrund:

Description: Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484). Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484). Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

Gene: HAX1

Molekulargewicht: 31kDa

Gen-ID: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization