Metabotropic Glutamate Receptor 5 Antikörper (PE-Cy5.5)

Produktnummer ABIN899794

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Metabotropic Glutamate Receptor 5 in WB. Er zeigt eine Reaktivität gegenüber Ratte, Human, Maus, Huhn und Hund.

Kurzübersicht für Metabotropic Glutamate Receptor 5 Antikörper (PE-Cy5.5) (ABIN899794)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reaktivität: Ratte, Human, Maus, Huhn, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 5 Antikörper ist konjugiert mit PE-Cy5.5

Applikation: Western Blotting (WB)

Produktdetails anti-Metabotropic Glutamate Receptor 5 Antikörper (PE-Cy5.5)

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Sheep,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse GRM5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:100-500)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Andere Bezeichnung: mGluR5

Hintergrund:

Synonyms: Glu5R, Gprc1e, mGluR5, mGluR5b, AI850523, 6430542K11Rik, Metabotropic glutamate receptor 5, Grm5

Background: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity (By similarity).

Molekulargewicht: 132kDa

Gen-ID: 108071

UniProt: Q3UVX5

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity