DOCK1 Antikörper (AA 465-550) (FITC)
Kurzübersicht für DOCK1 Antikörper (AA 465-550) (FITC) (ABIN894255)
Target
Alle DOCK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 465-550
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Kreuzreaktivität
- Maus
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Homologie
- Human,Rat,Dog,Cow,Sheep,Horse,Chicken
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DOCK1
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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Andere Bezeichnung
- DOCK1
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Hintergrund
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Synonyms: 180 kDa protein downstream of CRK, Ced5, Dedicator of Cytokinesis 1, Dedicator of cytokinesis protein 1, DOCK 1, DOCK-1, DOCK 180, DOCK1, DOCK1_HUMAN, DOCK180.
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1.Tissue specificity: Highly expressed in placenta, lung, kidney, pancreas and ovary. Expressed at intermediate level in thymus, testes and colon.
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Gen-ID
- 1793
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Pathways
- Signaling of Hepatocyte Growth Factor Receptor
Target
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