COMMD10 Antikörper (AA 91-190) (HRP)

Produktnummer ABIN891788

Der Kaninchen Polyklonal Anti-COMMD10-Antikörper wurde für ELISA, IHC (p) und IHC (fro) validiert. Er ist geeignet, COMMD10 in Proben von Maus zu detektieren.

Kurzübersicht für COMMD10 Antikörper (AA 91-190) (HRP) (ABIN891788)

Target: COMMD10 (COMM Domain Containing 10 (COMMD10))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COMMD10 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-COMMD10 Antikörper (HRP)

Bindungsspezifität: AA 91-190

Kreuzreaktivität: Maus

Homologie: Human,Rat,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COMMD10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu COMMD10

Target: COMMD10 (COMM Domain Containing 10 (COMMD10))

Andere Bezeichnung: COMMD10

Hintergrund:

Synonyms: COMM domain containing 10, COMMD 10, FLJ11285, HGNC:30201, HSPC305, PTD002.

Background: COMMD or COMM is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. The proteins designated as COMMD or COMM domain containing 1-10 are extensively conserved in multicellular eukaryotic organisms and define a novel family of structural and functional homologs of MURR1. The prototype of this family, MURR1/COMMD1, suppresses NFkB not by affecting nuclear translocation or binding of NF-kappaB to cognate motifs, rather, it functions in the nucleus by affecting the association of NF-kappaB with chromatin.

Gen-ID: 51397