CLK2 Antikörper (AA 401-499) (AbBy Fluor® 488)

Produktnummer ABIN891299

Der Kaninchen Polyklonal Anti-CLK2-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, CLK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CLK2 Antikörper (AA 401-499) (AbBy Fluor® 488) (ABIN891299)

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK2 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CLK2 Antikörper (AbBy Fluor® 488)

Bindungsspezifität: AA 401-499

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CLK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Andere Bezeichnung: CLK2

Hintergrund:

Synonyms: CDC like kinase 2, CLK 2, CLK kinase, Clk2 Scamp3, Dual specicity protein kinase CLK2, hCLK 2, hCLK2, MGC61500, Tu52, CLK2_HUMAN.

Background: CDC-like kinase 2 (CLK2) belongs to a family of autophosphorylating kinases termed CLK (CDC2/CDC28-like kinases), which have been shown to phosphorylate serine- and arginine-rich (SR) proteins of the spliceosomal complex, and to influence alternative splicing in overexpression systems. Recent findings demonstrated that the CLK kinases activate PTP-1B family members, and this phosphatase may be an important cellular target for CLK action. Mutations in the CLK2 proteins affect organismal features such as development, behavior, reproduction, and aging as well as cellular features such as the cell cycle, apoptosis, the DNA replication checkpoint, and telomere length.

Gen-ID: 1196

Pathways: Regulation of Carbohydrate Metabolic Process