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CLK2 Antikörper (N-Term)

CLK2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB3205 unconjugated
Produktnummer ABIN391766
  • Target Alle CLK2 Antikörper anzeigen
    CLK2 (CDC-Like Kinase 2 (CLK2))
    Bindungsspezifität
    • 15
    • 12
    • 9
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-30, N-Term
    Reaktivität
    • 60
    • 42
    • 28
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 74
    Kaninchen
    Klonalität
    • 74
    Polyklonal
    Konjugat
    • 23
    • 6
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CLK2 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 37
    • 13
    • 13
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This CLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CLK2.
    Klon
    RB3205
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product CLK2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Yoshida, Kim, Carver, Su, Weremowicz, Mulvey, Yamamoto, Brennan, Mei, Long, Yao, Polyak: "CLK2 Is an Oncogenic Kinase and Splicing Regulator in Breast Cancer." in: Cancer research, Vol. 75, Issue 7, pp. 1516-26, (2015) (PubMed).

    Nam, Seo, Park, An, Kim, Yang, Kim, Jeong, Jin: "Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation." in: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31157-63, (2010) (PubMed).

  • Target
    CLK2 (CDC-Like Kinase 2 (CLK2))
    Andere Bezeichnung
    CLK2 (CLK2 Produkte)
    Synonyme
    MGC53993 antikoerper, hclk2 antikoerper, clk2 antikoerper, fb20c02 antikoerper, si:ch211-81a5.7 antikoerper, wu:fb20c02 antikoerper, MGC131228 antikoerper, hCLK2 antikoerper, AU041688 antikoerper, Tu52 antikoerper, CDC like kinase 2 antikoerper, CDC like kinase 2 S homeolog antikoerper, CDC-like kinase 2a antikoerper, CDC like kinase 2 L homeolog antikoerper, CDC-like kinase 2 antikoerper, CLK2 antikoerper, clk2.S antikoerper, clk2 antikoerper, clk2a antikoerper, clk2.L antikoerper, Clk2 antikoerper
    Hintergrund
    This gene encodes a member of the CLK family of dual specificity protein kinases. CLK family members have shown to interact with, and phosphorylate, serine- and arginine-rich (SR) proteins of the spliceosomal complex, which is a part of the regulatory mechanism that enables the SR proteins to control RNA splicing. This protein kinase is involved in the regulation of several cellular processes and may serve as a link between cell cycle progression, apoptosis, and telomere length regulation.
    Molekulargewicht
    60090
    Gen-ID
    1196
    NCBI Accession
    NP_003984
    UniProt
    P49760
    Pathways
    Regulation of Carbohydrate Metabolic Process
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