N-Cadherin Antikörper (AA 701-800) (AbBy Fluor® 350)

Produktnummer ABIN889727

Der Kaninchen Polyklonal anti-N-Cadherin Antikörper wird verwendet zum Nachweis von N-Cadherin in Proben von Human. Er wurde validiert für WB, IF (p) und IF (cc).

Kurzübersicht für N-Cadherin Antikörper (AA 701-800) (AbBy Fluor® 350) (ABIN889727)

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser N-Cadherin Antikörper ist konjugiert mit AbBy Fluor® 350

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-N-Cadherin Antikörper (AbBy Fluor® 350)

Bindungsspezifität: AA 701-800

Verwendungszweck: N-cadherin Polyclonal Antibody, AbBy Fluor-350 Conjugated

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human N-cadherin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Andere Bezeichnung: N-cadherin

Hintergrund:

Synonyms: CDHN, NCAD, CD325, CDw325, Cadherin-2, Neural cadherin, N-cadherin, CDH2, CADH2_HUMAN

Background: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity).

Gen-ID: 1000

UniProt: P19022

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane